• NEW SUBMISSION PLATFORM

    Omni Akuatika
    We would like to inform that submission in Omni-Akuatika and all publishing process is now migrating to the Open Journal Systems management and publishing platform  (www.ojs.omniakuatika.net).

    For those who have submitted their paper before September 2016, we will take the necessary measure for being intregated in OJS system.



    Regards
    Agung Dhamar Syakti
    Editor-in-Chief Omni-Akuatika

oaj1

Downloads here
Overview Search Downloads Submit file Up
Download details



Potensi Rumput Laut Coklat Jenis Sargassum duplicatum yang berasal dari Perairan Menganti-Kebumen sebagai Antiagregasi Platelet


Dewanto, Siti Mutripah, Yoppi Iskandar dan Melisa Intan Barliana


1Fakultas Farmasi Universitas Padjajaran-Bandung
2Fakultas Biologi Universitas Jenderal Soedirman-Purwokerto


ABSTRACT


A study concerning the potential of brown seaweed of Sargassum duplicatum from Menganti beach-Kebumen as anti-platelet aggregation was investigated. Anti-platelet aggregation test performed in vitro using human blood with a Born method, is based on changes in light transmission with Adenosine Diphosphat (ADP) 10 μL added as an inductor. Tests performed on extracts and fractions of Sargassum duplicatum using positive control acetyl salicylic acid 80 mg / mL. The test results of the anti-platelet aggregation of Sargassum duplicatum extract concentration 125 μg /mL, 250 μg /mL, 500 μg /mL, n-hexane fraction 500 μg /mL, the ethyl acetate fraction 500 μg /mL, and water fraction 500 μg/mL, respectively gives a value of 4.68%, 6.77%, 11.64%, 55.51%, 52.10% and -1.55%. Whereas the positive control acetyl salicylic acid 8μug /mL give 48.49% inhibitory. based on these results it can be concluded that the fraction n-hexane of Sargassum duplicatum shows anti-platelet aggregation activity of the most optimal. Phytochemical test showed n-hexane fraction containing flavonoids, monoterpenoid, seskuiterpenoid, steroids and quinones.


Keywords: Sargassum duplicatum, Mengant, anti-platelet aggregation, ADP



(1 vote)

5272 Downloads so far.


Download Article here
Download





 Copyrigth and Licencing
Licence Creative Commons
Omni-Akuatika de Fisheries and Marine Science Faculty - Jenderal Soedirman University est mis à disposition selon les termes de la licence Creative Commons Attribution 4.0 International.
Fondé(e) sur une œuvre à www.omniakuatika.net.
Les autorisations au-delà du champ de cette licence peuvent être obtenues à www.omniakuatika.net

OmniAkuatika is Indexed and Abstracted by:

SmallLogo1

 

 

 

 

 

 

 

 

 


TodayToday94
YesterdayYesterday197
This_WeekThis_Week1090
This_MonthThis_Month2066
All TimesAll Times528091
Statistik created: 2024-09-13T12:33:25+07:00

counters!